Ali's(a.s) relation to the Qur'an is considered by the prophet(s.a.w) as one of companionship which is constantly set up until the Resurrection. This article seeks to expound the quality of the Qur'an's companionship with Ali(a.s). Possibilities available in this regard, various kinds of companionship, including unity and oneness; cause and effect relation; scientific, spiritual and natural relations,with proof from several verses and hadiths are discussed.